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化妆品中一氯乙酸和二氯乙酸的安全性评价
陆智1, 李亚杰, 李钟瑞2, 李霞
1.无限极(中国)有限公司;2.深圳天祥(Intertek)质量技术服务有限公司
摘要:
介绍了化妆品中一氯乙酸和二氯乙酸的来源途径、危害分类及法规限值。通过计算理论最高安全 限值,对化妆品中的一氯乙酸和二氯乙酸分别进行了安全性评价。结果显示当一氯乙酸在不同类 型化妆品中的平均含量不超过12 mg/kg时理论上不会对消费者造成显著的毒理风险;二氯乙酸的 理论最高可接受限量临时值可设为4.3 mg/kg,长期目标可设为0.7 mg/kg。
关键词:  化妆品  一氯乙酸  二氯乙酸  风险评估  理论最高安全限值
DOI:10.13222/j.cnki.dc.2017.02.001
分类号:
基金项目:
Risk assessment of monochloroacetic acid and dichloroacetic acid in cosmetics
LU Zhi1, LI Ya-jie, LI Zhong-rui2, LI Xia
1.Infinitus (China) Company Ltd.;2.Intertek Testing Services Shenzhen Ltd.
Abstract:
The source, hazard classification and regulatory limits of monochloroacetic acid and dichloroacetic acid in cosmetics were introduced. By calculating the theoretical maximum acceptable limit, their risks were evaluated in cosmetics. The results indicated that the average concentration of monochloroacetic acid in cosmetic up to 12 mg/kg did not pose significant health risk to customers. The theoretical maximum limit of dichloroacetic acid could be set at 4.3 mg/kg, and 0.7 mg/kg as its long-term objective
Key words:  cosmetics  monochloroacetic acid  dichloroacetic acid  risk assessment  theoretical maximum limit

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