| 黑色素形成机理的新概念及复合美白剂的应用 |
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| 引用本文： | 江志洁,朱育新.黑色素形成机理的新概念及复合美白剂的应用[J].日用化学品科学,1998(4):3-5. |
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| 作者姓名： | 江志洁 朱育新 |
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| 作者单位： | Jiang Zhijie Zhu Yuxin Wu Qiying Zhang Fengxiang |
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| 摘 要： | 多年来，人们认为酪氨酸酶是黑色素生物合成所须的唯一的酶。９０年代中期的新概念认为，多巴色素互变酶和ＤＨＩＣＡ氧化酶也影响黑色素的合成。同时，黑色素细胞外的内皮素刺激黑色素细胞的增殖，分化并激活酪氨酸酶的活性。
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| 关 键 词： | 黑色素 内皮素 拮抗剂 美白剂 化妆品 护肤品 |
The New Concept for the Mechanism of Melanogenesis and Application of Complex Lightener |
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| Abstract: | For a long time,people consider that the tyrosinase is the only enzyme which required for the bio-synthesis of melanin.It is until the middle of the nineties,a new concept emerged and considered that both dopachrome tautomerase and DHICA oxidase also play a role in the course of melanin synthesis.At the same time the endothelin located outside the melanocytes excites the proliferation of melanocytes, and activates the activity of the tyrosinase.Therefore,the multiple application of the endothelin antagonist and lighteners of other kinds will be a new direction for the research and development of the lightening cosmetics of a new era. |
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